Sentence examples for further contributing to the activation of from inspiring English sources

Therefore, levels of both WNK1 and WNK4 may be increased in the kidneys of patients with PHAII carrying the KLHL3 and Cullin3 mutations, further contributing to the activation of OSR1/SPAK NCC signaling and explaining the more severe PHAII phenotypes evident with Cullin3 and KLHL3 mutations than with WNK1 and WNK4 mutations (Boyden et al., 2012).

The diminished ML may imply a lower level of serotonin and further contribute to the activation of HPG axis and suppression of HPA axis.

Products of lipofuscin photooxidation in RPE cells also serve as triggers for complement activation, further contributing to the chronic localized inflammation (Zhou et al. 2006).

One or more of these changes could contribute to the activation of σB during exponential growth and further experiments will be required to identify the specific signal involved.

These results further suggest that HOI-02 exerts its effects by generating ROS, which then contribute to the activation of key apoptosis-related proteins.

Further studies need to establish whether concomitant mutations or amplifications of other EGFR signalling pathway genes may contribute to the activation of this pathway in GC.

These data indicate that NTG induces oxidative stress, which contributes to the activation of Nrf2/ARE pathway.

There are likely other factors that contribute to the activation of Uch37 by Rpn13.

PKC activation contributes to the activation of MAPK, most probably via c-Raf-1 activation.

Subsequently, C5a contributes to the activation of the stress system.

PIP3 is essential for the activation of Akt and contributes to the activation of Btk.