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Further complexity arises from differences in clinical practice and, i.e., the course of oxygen support.
Further complexity arises from the fact that the transcription and expression patterns of PfRH ligands vary between different parasite lines [8], [24].
Further complexity arises from the fact that effector Th cells may secrete combinations of cytokines and exhibit functional plasticity.
A further complexity arises from the longitudinal nature of the data, which needs to be taken into account when imputing.
Further complexity arises from splicing and posttranslational modification of some components (e.g. see Dudognon et al. 2004; Salama et al. 1997; Stankewich et al. 2006).
Further complexity arises from the great heterogeneity of molecular lesions found in human tumors [ 4], which is only now becoming fully appreciated.
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Notably, further complexity arose with the identification of RAS effectors (e.g. RASSF1-2 or NORE1) with putative tumor suppressor, rather than oncogenic functions [18].
Each class also contains isoforms that exhibit different binding affinities for IgG subclasses, and further complexities arise from their differential expression on host cell populations and the presence of variant alleles in the low-affinity II and III receptor subtypes [ 12].
While the choice between relative and absolute inequality is already value laden, further complexities arise when, as is often the case, health variables have both a lower and upper bound, and thus can be expressed in terms of either attainments or shortfalls, such as for mortality/survival.
Further distributional complexity arises because southern and western European populations are mainly sedentary, whereas northernmost European and East Asian populations migrate between northern breeding grounds and southern wintering areas [ 5].
For GM organisms, a further dimension of complexity arises.
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CEO of Professional Science Editing for Scientists @ prosciediting.com