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Ignacio Martín-Loeches, Paula Ramirez, Jordi Rello, Raul Ortiz de Lejarazu, David Kelvin and Jesus F Bermejo-Martin In a viral infection with a short period of incubation and a limited clinical course, the early immune response to the virus should be key to determining further clinical evolution.
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It is now undergoing further clinical development.
Further clinical development is ongoing.
They could be further refined to better understand clinical evolution and pathomechanisms of the disease and might provide additional important information in evaluating outcome measures of future therapeutic studies.
Because of the satisfactory clinical evolution and because a further intervention was not envisaged for this animal, no further examinations were undertaken to differentiate scar tissue from possible recurrence of a fluid-filled cyst.
Confirmation of the diagnosis merely relies on clinical evolution, which may lead to unnecessary treatment and further complications.
These results suggest more complex relationships between the impaired neutrophil chemotaxis and the clinical evolution of the burn patients could be uncovered in further studies.
Spontaneous clinical recoveries and relapses are a common feature of IKC in sheep [ 4], which agrees with the clinical evolution of the two positive sheep from the Pyrenees sampled twice, further suggesting the role of sheep as a maintenance host of M. conjunctivae in this area, as previously suggested in Switzerland assessed by serology [ 7] and Central Pyrenees [ 12].
Further studies are therefore warranted to better understand and investigate the characteristics of this particular clinical evolution of patients with breast cancer and, thus, to more effectively treat these patients.
But further clinical research is needed to see if the findings can be applied in a clinical setting, Hallstrom added.
Further clinical studies are necessary.
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