Sentence examples for further clinical developments from inspiring English sources

The efficacy and design of this immunotherapeutic approach render the strategy very attractive for further clinical developments.

However, only one study has progressed beyond the phase I or II stage, as further clinical developments are challenging.

Further, clinical developments of CXR4 antagonists have been delayed in preclinical and clinical studies due to serious side effects (cardiac abnormalities and liver toxicity) or lack of drug efficacy.

In vitro pharmacokinetic studies have suggested that CA-1-P is transformed into a more reactive metabolite than CA-4-P, which is responsible for most of the antitumoral activity; this has formed the basis for further clinical developments of the drug as an antivascular and antitumor agent [ 77].

It is now undergoing further clinical development.

However, the insufficient metabolic stability of 3 limits its further clinical development.

Initially his deficit was setted as traumatic but further clinical development proposed again the diagnostic doubt.

The characteristics of compstatin suggest that this peptide and its analogs could be attractive candidates for further clinical development.

Furthermore they inhibit both early and late steps of the replication cycle which increases their potential for further clinical development.

We conclude that GMZ2 is a safe and immunogenic malaria vaccine candidate suitable for further clinical development.

This review aims to highlight candidates with potential for further clinical development based on their putative modes of action.