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Physicians might have detected the risk of further clinical deterioration before qSOFA was determined as positive.
With further clinical deterioration, select patients may be candidates for ventricular assist devices and heart transplants.
Urgent and appropriate antibiotic administration is mandatory to prevent further clinical deterioration, especially in critically ill patients with signs of respiratory distress or severe sepsis.
Because of progressive tachypnea and the suspicion of progressive sepsis, antibiotic therapy was switched to a third-generation cephalosporin and subsequently to meropenem the next day because of further clinical deterioration.
It is important to derive a rapid diagnostic work-up to determine cause of clinical deterioration as well as specific management to prevent further clinical deterioration and death.
It is important to derive a rapid diagnostic work-up to determine the cause of clinical deterioration as well as specific management to prevent further clinical deterioration and death.
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Concurrent pulmonary emboli, as suggested by early case reports from hospitalized patients with pandemic influenza A H1N1v 2009 in the US [ 13], may further contribute to clinical deterioration in some patients.
If such studies confirm that specific rapid declines in protein C levels can be readily detected, and further that they precede clinical deterioration, this information could be used to guide therapy.
It may be that these patients would present clinically over time irrespective of ICF but our aim was to detect these earlier before clinical deterioration and further onwards transmission.
Lack of response to anti-tubercular therapy and clinical deterioration led to further investigations, which came out positive for sarcoidosis.
Three strains (two strains of patient 3, one strain of patient 5) were further analysed - prompted by the clinical deterioration of these patients after Trichosporon detection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com