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We suggest that further assays should be performed using more accurate methods to characterize new molecules with antiviral activity that may result in new drugs.
However, further assays should be conducted to test if the catalytic activity of the DDE motif remains active.
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Given the fact that many promising new assays for CTC detection are in development [ 28], further evaluation of these assays should also include their validation in a relevant clinical setting with sufficient follow-up information and OS as the objective endpoint.
The collected serum was stored at –20°C for further assays.
The collected sera were stored at −20°C for further assays.
Which assays should be used?
Further investigations, such as complementation assay, should be considered to demonstrate clearly the mechanisms of capsular loss in this particular isolate [ 44].
For example, the semen/saliva duplex assay should be further optimized in order to reduce or eliminate artifacts such as the broad peaks/humps observed in the HTN3 region arising from the TGM4 melt curve.
Patients who test positive by a functional assay should then be further studied with the DNA test for confirmation and to distinguish heterozygotes from homozygotes.
Authors' conclusions are that further studies 'should examine whether FGF23 assay should be included in routine clinical evaluation of CKD, as part of CV risk stratification'.
Further cell-cased assays should be implied to determine the change in PABPN1 levels in different cell types.
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