Sentence examples for further ascertain a from inspiring English sources

In order to further ascertain a possible link between TIMP-1 effects and a signalling cascade in relation with actin polymerisation and depolymerisation, we sought for changes in the phosphorylation of cofilin, an actin binding protein that depolymerises actin and looses this capacity upon phosphorylation.

This further ascertained a dose-dependent effect of trehalose octasulfate, which may enable to set its optimum dosage.

To further ascertain whether TFEB is a substrate of SIRT1, we carried out in vitro deacetylation assay with purified SIRT1 and acetylated Flag-tagged TFEB (Fig. S3E).

To further ascertain whether Necdin acts as a functional effector of Gαo, experiments were performed using two different cell types: (1) 293T and Neuro2a cells transfected with plasmids encoding Gα and Necdin, and (2) U87MG cells endogenously expressing CB1R, which triggers the Gi/o-mediated signaling pathway upon activation.

To further ascertain the similarities between NLP and NB, a detailed morphological analysis was performed on the precipitates generated.

To further ascertain if PDGF-driven fibroblast recruitment is a key mechanism driving the differential wound repair response, we assessed the effect of PDGF neutralization on fibroblast migration at 72 h post injury.

To further ascertain the physicians' use of the antibiotic treatment guideline, we presented a scenario for a case of community-acquired pneumonia (Appendix).

To further ascertain the degree of involvement of eNOS in the cardioprotective effects of Ad-SIRT1, NOS inhibitor L-NAME was administered after adenoviral injection.

To further ascertain the role of p68 in invasion of cancer cells, a matrigel invasion assay was performed with Wnt3a-MCF7 cells.

A larger cohort of patients is needed to further ascertain the toxicity of this accelerated partial breast regimen.

To further ascertain the underlying mechanisms, we [ 70] examined transcriptomic changes in a trial of paediatric patients with the tetralogy of Fallot causing cyanosis undergoing corrective cardiac surgery.