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The compounds of triazoles and CAA might be the multisite inhibitors for antifungal activity, the 6 carbons in the alkyl chain are optimal for the fungicidal activity, so CTE could not be easier for fungi to develop resistance with a different mode of action [13].
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This gives the fungus time to develop resistance to the drug by becoming able to quickly replace the fungal proteins the drug destroys, or to efficiently remove the drug from its cells.
Yeast and fungi are able to develop resistance to counteract the action of azoles.
The fact that microorganisms among which fungi nowadays tend to develop resistance towards drugs, coupled to the undesirable side effects of certain antibiotics is a real problem of concern.
Triazoles act as surface protectants and enter plant tissues as systemic fungicides, but it was site specific inhibitors and easier to develop resistance for fungi [16].
East Anglia is spearheading the fight to beat Ash Dieback fungus with a planting scheme designed to develop resistance against the disease.
Some cancers will always find a way to develop resistance.
Has the malaria parasite started to develop resistance?
Another concern was that the virus seemed to mutate to develop resistance to the drug.
"With multiple molecules, bacteria often have to develop resistance to each one.
The first malaria mosquito to develop resistance to DDT was Anopheles saccharovi, in Greece.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com