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Because the transcription machinery is fundamentally conserved in the eukaryotic lineage, this framework is potentially applicable to higher eukaryotes including humans.
However, although the cell types for lipid storage are different, compositions of lipid (such as saturated or unsaturated fatty acid, triglyceride) and metabolic pathways are fundamentally conserved beyond species.
The manifestation of distinct sexes is fundamentally conserved among most metazoans.
Striated muscle formation is a fundamentally conserved process and requires the highly regulated and ordered expression of sarcomeric proteins and their assembly into the sarcomeric contractile unit [ 4].
Despite operational differences, previous studies had revealed that canonical functions of segmentation genes are fundamentally conserved between long germ and short germ segmentation (Mito et al., 2005; Mito et al., 2006; Mito et al., 2007).
There are seven known human STAT isoforms that share a fundamentally conserved multi-domain architecture composed of an N-terminal dimerization domain [ 62], a core consisting of a coiled-coil domain, DNA-binding domain, Src2 Homology domain (SH2) [ 63- 65], and a C-terminal transactivation domain [ 66].
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Farmers are fundamentally committed to conserving and enhancing the biodiversity on their farms".
This fine-scale geographic differentiation enhanced assignment to region of origin, and through the identification of adaptive diversity, fundamentally changes how these populations should be conserved.
More fundamentally, the evolution of hypervariable core sequences within very highly conserved DNA sequence backgrounds has not been examined.
Genetic analyses of zebrafish heart revealed many fundamentally important molecular pathways underlying its formation and function, which are conserved among all vertebrates including human [3] [5].
Among fungi that produce a given secondary metabolite, the underlying gene clusters are generally highly conserved, making it unlikely that C. zeae-maydis possesses a fundamentally different mechanism responsible for cercosporin biosynthesis.
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