So although legal cynicism may be less applicable or fundamentally different in non-US or rural contexts, e.g. the role-taking process through which a relevant local cultural frame influences appraisals of behaviour is a general process (Mead 1934) and, therefore, likely has explanatory power, regardless of the larger context.
"But what happens is that a lot of the techniques that apply to email are not really applicable to push notifications…We believe, fundamentally, that companies can make more money by sending fewer, but better messages," he adds.
We argue that trials targeting healthy humans are often fundamentally flawed owing to inappropriate use of paradigms only applicable to populations with overt clinical disease and the consequent misleading (typically negative) results can severely retard advancement of drug development.
"Allowing a corporation, through either shareholder vote or board resolution, to take on and assert the religious beliefs of its shareholders in order to avoid having to comply with a generally-applicable law with a secular purpose is fundamentally at odds with the entire concept of incorporation," Verrilli argued in the brief.
Because the transcription machinery is fundamentally conserved in the eukaryotic lineage, this framework is potentially applicable to higher eukaryotes including humans.
These tools have fundamentally changed our understanding of the catalytic power of peroxiredoxin systems and should also be widely applicable for improving quantitative assay capabilities in other electron transfer systems.
Parsimonious GIUH models of surface runoff that use this hydrologic connectivity have the advantage of low data requirements, being scalable and applicable regardless of the spatial complexity of the hillslope, and have the potential to fundamentally improve flood forecasting tools used in the assessment of ecosystem services.
However, the procedure for generating RNA-seq data is fundamentally different from that for microarray data, the normalization methods used in microarray data are therefore not directly applicable in RNA-seq data.
More fundamentally, OR-based assessments require investment in the collection, storage, and accessibility of valid, current data to yield accurate and applicable conclusions.
The accounting office concludes, however, that even if all of the applicable regulations had been followed, security risks would still exist because the department's "regulations, policies and procedures are fundamentally flawed".
