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All the information available from animal and human investigations indicates that lactate production and metabolism are two extraordinarily complex processes found in almost every organ, and that are perhaps as fundamental to intermediate metabolism as the generation and consumption of glucose.
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The calcium ion (Ca2+) is a signalling intermediate fundamental to many aspects of mammalian physiology and influences processes ranging from fertilisation to cell death, modulation of gene transcription, ion channel function, exocytosis and phospholipid metabolism [1].
Detailed knowledge on serpin structure and dynamic behavior (intermediate conformations, conversion to latency, polymerization) is fundamental to design molecules for the treatment of diseases dependent on serpin polymerization [29].
Strong professions are fundamental to economic development.
That's absolutely fundamental to us".
It is fundamental to our national security.
This conception was fundamental to Leninist thought.
"Water is something fundamental to our existence".
It is basic and fundamental to life.
Again, this is fundamental to the row.
Free trade is fundamental to prosperity.
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