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Cadherin-2 plays a fundamental role during zebrafish CNS and heart morphogenesis.
EMT is therefore thought to play a fundamental role during the early steps of invasion and metastasis of carcinoma cells.
Taken together, we provide insight into the mechanisms by which KATNB1 mutations cause human cerebral cortical malformations, demonstrating its fundamental role during brain development.
Neuregulin 1 (NRG1) is a multifunctional and versatile protein: its numerous isoforms can signal in a paracrine, autocrine, or juxtacrine manner, playing a fundamental role during the development of the peripheral nervous system and during the process of nerve repair, suggesting that the treatment with NRG1 could improve functional outcome following injury.
Spontaneous bursts play a fundamental role during neuronal development [8].
Thus, the oscillating, caudal domain may be an evolutionary novelty of higher vertebrates, and the more widely conserved stripe domain may fulfil a more fundamental role during segmentation.
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In the present study, seven phosphatases were identified to perform fundamental roles during conidial germination on saccharide and alcohol carbon sources, broadly influencing morphological adaptations, metabolism, and cell cycle (Table 6).
Dynein also plays fundamental roles during mitosis, with force generation of microtubule‐associated motors required for breakdown of the nuclear envelope, alignment of the spindle and regulation of the spindle assembly checkpoint (Bader & Vaughan, 2010).
The low level of etv7 expression in multiple tissues might indicate a fundamental role of etv7 during both development and adulthood.
In addition to single-stress defence reactions, it is possible that there is a fundamental role for P5ßR enzymes during plant development because an Arabidopsis thaliana (L).
Our findings reveal a fundamental role for Tie1 signaling during lymphatic vessel remodeling and valve morphogenesis and implicate it as a candidate gene involved in primary lymphedema.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com