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Epigenetic modifying factors are fundamental regulators of chromatin structure and gene expression during development and differentiation through the induction of chemical modifications on histones, DNA or via remodeling of the chromatin structure.
These observations emphasize the importance of ECM properties as fundamental regulators of stem cell fate and demonstrate that known variation in these properties can have a profound affect on undifferentiated stem cell behavior.
Plks are fundamental regulators of the cell cycle.
Many fundamental regulators of metabolic physiology reside within the endocrine and neuroendocrine systems of the body.
Endosomal trafficking pathways are emerging as fundamental regulators of the wall physiology, involved in multiple signaling pathways and developmental processes.
β-Arrestins are fundamental regulators of seven transmembrane domain receptor (7TMR) signalling, co-ordinating temporal and spatial response characteristics.
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The microtubule affinity regulating kinase (MARK) family of enzymes is another fundamental regulator of MAP activity.
Cdc42, a member of the Rho GTPase family, is a fundamental regulator of the actin cytoskeleton during cell migration.
The role of Fbxl3 as a fundamental regulator of CRY protein has been confirmed by a complementary work on a different mouse model, overtime 21.
Carbon exchange between the Earth's surface and atmosphere is a fundamental regulator of the climate system.
RpoS is known to be a fundamental regulator of general stress responses to various stress conditions in E. coli [17], [18], [21], [22].
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