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The microtubule affinity regulating kinase (MARK) family of enzymes is another fundamental regulator of MAP activity.
Carbon exchange between the Earth's surface and atmosphere is a fundamental regulator of the climate system.
Cdc42, a member of the Rho GTPase family, is a fundamental regulator of the actin cytoskeleton during cell migration.
RpoS is known to be a fundamental regulator of general stress responses to various stress conditions in E. coli [17], [18], [21], [22].
Moreover, we recently demonstrated that, in postnatal testis, ATRA increases meiotic entry of differentiating spermatogonia in vitro by activating the Kit signalling pathway [10] and by stimulating a significant increase of Stra8, a fundamental regulator of meiosis in both female and male mice [11] [12].
In the intestinal tract, energy status is a fundamental regulator of epithelial cell metabolism [ 3].
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Epigenetic modifying factors are fundamental regulators of chromatin structure and gene expression during development and differentiation through the induction of chemical modifications on histones, DNA or via remodeling of the chromatin structure.
These observations emphasize the importance of ECM properties as fundamental regulators of stem cell fate and demonstrate that known variation in these properties can have a profound affect on undifferentiated stem cell behavior.
Plks are fundamental regulators of the cell cycle.
Many fundamental regulators of metabolic physiology reside within the endocrine and neuroendocrine systems of the body.
β-Arrestins are fundamental regulators of seven transmembrane domain receptor (7TMR) signalling, co-ordinating temporal and spatial response characteristics.
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