Collectively, our findings of distinct fate of TBBPA in different acid leaching reagents provided fundamental information for design of hydrometallurgical treatment of e-wastes to minimize acid reactions with BFRs within plastics matrix and to maximize acid leaching efficiency for metals recycling processes.
Such probes are valued reagents in both fundamental and applied biological research and are key tools in drug discovery that allow preclinical target validation in both academic and industrial laboratories.
The fundamental limitation of small-molecule reagents is encoded in the name itself: the molecules are small and thus intrinsically unable to compete with the relatively large contact surfaces found at many biologically important ligand receptor interfaces, such as protein protein interactions.
A fundamental understanding of complex mineral-reagent interactions on micro and nano scales will be developed through this collaborative research, thus helping mineral companies, such as Vale Inco and Newmont to make value added products.
The design and discovery of these novel reagents provide valuable tools to probe fundamental questions about a particular protein-protein complex, and may lead to a new generation of potential therapeutic agents.
1, 2 Most methods for the installation of this fundamental building block use either highly toxic and/or explosive reagents, which are usually nucleophilic sources of azide.
The technique described herein provides a robust tool developed from coupling two fundamental assays for investigating the effects of various metabolites, reagents, ligands, and substrates on the mechanisms of Ca2+ sequestration within the ER.
An understanding of the nature of immune protection and the role of immune effector products such as interferon-γ (IFN-γ) in the control of infectious disease is fundamental to the rational design of effective vaccines and immunotherapeutic reagents.
The knowledge of the specificity and affinity of GBPs is essential for illuminating the inner workings fundamental to glycobiology, and in the design of glycan-targeting reagents and therapeutics.
This strobing of the transition-state region between reagents and products provides real time observations that are fundamental to understanding the dynamics of the chemical bond.
