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Although Ktrans is a complex function of tumour blood flow, endothelial surface and endothelial permeability (Tofts et al, 1999), an effective agent will be expected to reduce some or all of these fundamental physiological parameters and it should therefore decrease Ktrans.
The rodent model presented here, what we term as the 'rapid onset of diabetes' (ROD) model, clearly exaggerates the fundamental physiological parameters that are typically observed in individuals with T2DM who might have chronically elevated GC levels and who may consume an energy dense 'westernized' HFD.
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Quantitative measurement of the regional cerebral blood flow [rCBF] is a fundamental physiological parameter for characterizing the status of the brain tissue.
Using computer vision, Zea counts plants, measures plant spacing, builds canopy height distributions and measures key physiological parameters — all based on imagery.
The model presented in this paper, in contrast, uses parameters that are derived from fundamental physiological properties and can be quantitatively obtained from metabolic measurements.
An analytic bifurcation analysis of this model provides fundamental insight into how oscillatory states depend on the physiological parameters of the model.
Such data have not been previously reported in the setting of clinical trial, where fundamental changes are made to conditions with simultaneous measurement of downstream physiological parameters.
"On the screen, she or he can see all the data regarding the patient — physiological parameters, E.C.G.s," he said.
Optimal CSF production relies on sustained physiological parameters in the anesthetized animal.
Figure 1: Effect of heat stress and heterotrophy on the main physiological parameters of Stylophora pistillata.
These characteristic structures of the lipids seem to contribute to their fundamental physiological roles in hyperthermophiles.
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