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Heme (Fe2+ protporphyrin IX) is a ubiquitous and essential tetrapyrrole molecule that performs a wide array of fundamental physiological functions, including oxygen transport, electron transfer, and transcriptional regulation.
By decreasing body temperature and slowing down heart and respiratory movements, along with some other fundamental physiological functions, torpor allows adult healthy shrews to reduce their energy expenditure during daylight hours [50].
Each isoform participates in fundamental physiological functions in the nervous, immune, and cardiovascular systems.
Circadian rhythms govern a number of fundamental physiological functions in almost all organisms, from prokaryotes to humans.
How the hypothalamic Hcrt neurons regulate diverse and fundamental physiological functions and what is the molecular mechanism that controls sleep are largely open questions.
cAMP (cyclic AMP) impacts on many aspects of the lives of eukaryotic cells to regulate numerous fundamental physiological functions [ 1, 2].
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Enabling the diffusive exchange of alveolar gases with pulmonary blood is the most fundamental physiological function of the lungs.
The fundamental physiological function of colonocytes is secretion, which involves many ribosomes, as evidenced by electronic microscopy.
In summary, our data confirm a fundamental physiological function of a distinct population of catecholaminergic C1 neurones of the RVLM.
Numerous studies have demonstrated that Wnt ligands via their cell membrane bound receptors and coreceptors exert many fundamental physiological and pathophysiological functions in multiple organs and cell lineages, including organogenesis, tumorigenesis, and fibrosis, among others [ 15].
We describe here how these extracellular nanoparticles were discovered and how it became gradually apparent that they play fundamental roles in regulation of physiological functions and pathological processes.
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