Sentence examples for fundamental pathways have from inspiring English sources

Transcellular transport is essential for transmucosal and plasma-to-tissue drug delivery by nanoparticles, whereas its fundamental pathways have not been fully clarified.

Metabolites involved in fundamental pathways have often been well studied and tend to be easily detected in the profile.

Over the past two decades, the successful development of tyrosine-kinase inhibitors (TKIs) that disrupt several fundamental signaling pathways has marked a notable advance in the fight against cancer.

This raises the fundamental question of whether signaling pathways have developed specialized architectures that overcome retroactivity and transmit unidirectional signals.

Kidney differentiation involves complex interactions between epithelial and mesenchymal cells, and signal transduction pathways have a fundamental role in controlling cell cell interactions.

Cell culture experiments have indicated that PrPC and in particular its N-terminal octarepeat region together with the phosphatidylinositol 3-kinase (PI3K /Akt signaling pathways have a fundamental involvement in neuroprotection and oxidative stress reactions.

Pathways have proven to be fundamental in understanding the role of genes in biological processes.

PI3K/AKT and MEK/ERK pathways have pivotal role in fundamental cellular functions such as cell proliferation, cell growth, and survival by phosphorylating a variety of substrates.

Importantly, Wnt signaling pathways have also been demonstrated to be of fundamental importance for the biology of dopaminergic neurons in the ventral midbrain (42– 42).

Components of the eicosanoid pathway have a fundamental role in the development of inflammation.

Traditionally, two pathways had been imagined.