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There are no fundamental obstacles of interest to such an agreement, but it will require great diplomatic skill and significant trust between countries to deliver; neither of which is yet apparent in the current negotiations.
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This is clearly a fundamental obstacle of determining the true model parameters from measurements even if the selected model structure is considered to be correct.
It is looking at concepts for partially or fully automated freight vessels, and recently reported that it has "not found any fundamental obstacles to the introduction of unmanned ships".
Tells about the Grand Challenges, a series of fourteen fundamental obstacles to scientific progress, such as developing vaccines that require no needles… Malaria, the world's most prevalent parasitic disease, kills as many as three million people every year-almost all of whom are under five, desperately poor, and African.
Mr. Nishi, a former director of research at Texas Instruments, said he did not see any fundamental obstacles to manufacturing the chip that I.B.M. would not be able to overcome.
At a high level, this reflects the fundamental obstacles to gun reform ingrained in American society.
Overcoming these fundamental obstacles to a two-state agreement requires more than negotiations between political leaders.
Yet, fundamental obstacles to global innovation flow, too, remain strong.
We become incapable of recognising that the fundamental obstacle to addressing our global challenges is that we see enemies everywhere.
It could be argued that RDF representations are inherently assertive [ 26], which poses a fundamental obstacle to its use in the elaboration of terminology.
Moreover, as I suggested in my paper, they also tend to reproduce harsh judgements about the deservingness of immigrants, which is a fundamental obstacle to inclusive solidarity.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com