Sentence examples for fundamental negative regulator from inspiring English sources

Among these, the histone methyltransferase EZH2 is a fundamental negative regulator of myogenic precursor differentiation by repressing the expression of myogenic genes through the H3K27me3 mark deposition on the promoters of myogenic genes [ 22, 28].

MiR-142-3p walsolso identified as a key negative regulator of IL-6.

mTOR is the key negative regulator of autophagy [ 4].

MTORC1 is a key negative regulator of autophagy.

Conversely, the negative regulator GSK3β was down-regulated.

BCL11A has been shown to be a critical negative regulator of γ-globin and fundamental to the 'fetal switch' from γ- to β-globin expression [58].

Among these pathways, sacy-1 acts as a strong negative regulator of meiotic maturation and provides a mechanistic connection to the fundamental germline processes of sex determination and gamete maintenance.

Second, the data show fundamental difference in LynA vs LynB, suggesting that LynA is responsible for positive signaling while LynB is responsible for negative regulator signaling.

Myostatin (MSTN) is a negative regulator of skeletal muscle mass.

Spl11 encodes an E3 ubiquitin ligase that functions as a negative regulator of programmed cell death.

OsMKP1 has been shown to be a negative regulator of the wound response in rice.