Sentence examples for fundamental in regulating from inspiring English sources

Chromatin architecture is fundamental in regulating gene expression.

Our results suggest that both these regions play a key role in the attention and executive function during cognitively demanding tasks and may be fundamental in regulating the balance between other brain regions.

Being associated with most human and mouse genes in all conserved co-expression clusters of the ESC-critical pathways, the FRE appears to be evolutionary conserved and hence fundamental in regulating transcriptional modulation important to ESC development.

However, whether the function of this conserved MST-FOXO signaling pathway is fundamental in regulating any pathophysiological process in vivo is still not well understood.

However, all of these pathways are fundamental in regulating the trade-off between survival and maintenance vs. growth, particularly in skeletal muscle where age-associated losses in SkM mass and function are observed with advancing age.

Voltage- gated sodium channels (VGSCs) are fundamental in regulating the excitability of neurons and overexpression of these channels can produce abnormal spontaneous firing patterns which underpin chronic pain [ 14, 15].

Disabled apoptosis has been catalogued among the fundamental hallmarks of cancer and the proteins of the Bcl-2 family play a fundamental role in regulating this modality of cell death.

Inhibition of HDACs represents a new strategy in human cancer therapy since these enzymes play a fundamental role in regulating gene expression and chromatin assembly.

Nuclear transport mechanisms play a fundamental role in regulating the activity of transcription factors [57].

In eukaryotes, DNA methylation plays a fundamental role in regulating the structure and activity of DNA and chromatin [3] [4].

Both Pten and Lkb1 play fundamental roles in regulating this pathway, and mutations of both genes are associated with neoplasia.