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We found no clear evidence of a fundamental impairment in anterior prefrontal 'branching processes' in patients with depression.
This may indicate a fundamental impairment of attention in schizophrenia [ 32], observed also in patients and family members who otherwise perform well.
They suggested these features might be characteristic of the disease as such, reflecting a fundamental impairment in the activation and regulation of cortical activity from subcortical structures.
This hypothesis suggests that some impairment evident in ASDs, such as the well-documented face-processing impairment, are not fundamental, but are secondary to the fundamental impairment in social motivation.
Goldman-Rakic had predicted this finding in her earlier writings (Goldman-Rakic 1991), saying "a defect in working memory the ability to guide behavior by representations may be the fundamental impairment leading to schizophrenic thought disorder" (Goldman-Rakic 1994).
Deficiency in type 1 and 3 IFNs following viral infection in asthma is proposed to be a fundamental impairment in the innate immune response promoting persistence of a viral infection and the development of an exacerbation of asthma.
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A framework is developed for modeling the fundamental impairments in optical datacenter interconnects, i.e., the power loss and the receiver noises.
Autism spectrum disorders (ASD) are a collection of etiologically diverse and overlapping syndromes that share the core diagnostic features of fundamental impairments in reciprocal social communication and highly restricted interests and/or repetitive behaviors.
Regarding face perception, all prosopagnosics showed fundamental impairments in recognizing famous people if based on visual cues only.
Unsustainable growth in program costs and beneficiaries, together with a growing recognition that even people with severe impairments can work, led to fundamental disability policy reforms in the Netherlands, Sweden, and Great Britain.
Our results suggest that source-monitoring deficits are part of a fundamental episodic memory impairment in schizophrenia.
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