Sentence examples for fundamental functional importance from inspiring English sources

The position of the turns appears to be evolutionary conserved among different species, as shown by a multiple sequence alignment of seven vertebrate shrew-1 homologues, suggesting a fundamental functional importance of this region (Suppl. Figure S1).

The PLAD-based model for the formation of TNFSF ligand3 TNFRSF receptor3 complexes alone, however, does not adequately explain one fundamental observation of overwhelming functional importance namely why a significant fraction of TNFRSF receptors bind soluble TNFSF ligands with high affinity but nevertheless fail to efficiently activate receptor-associated signaling pathways.

At the same time, the correct assessment of an individual's MHC constitution is the most fundamental pre-requirement to address the functional importance of MHC allelic diversity in evolutionary ecology, pathogen resistance and conservation.

The fundamental role of the octanoyl chain on Ser3 and the aromatic group of Phe4 in membrane-binding strikingly resembles the importance of these two residues for ghrelin function, suggesting a functional importance of ghrelin binding to membranes.

Its sensory system was designed to provide proprioceptive information as well as to emulate fundamental functional properties of human tactile mechanoreceptors of specific importance for grasp-and-hold tasks.

The ubiquitous expression pattern may be taken as another indication of the functional importance of Acdp proteins in fundamental biological processes in addition to the sequence conservation in evolutionarily divergent species.

A fundamental distinction between CME in yeast vs. mammalian cells has been the relative functional importance of clathrin and actin in these two systems.

In view of the functional importance of intra-islet communication, the spatial architecture of their edges may prove fundamental for coordinating physiological insulin secretion.

Species-specific microRNA expansion could have functional importance, and it has been demonstrated recently that an expanded microRNA cluster is fundamental to the maintenance of embryonic stem cell development in mice [ 13].

The inverse relationship between functional importance and evolutionary rate, sometimes regarded as the first principle of molecular evolution, has played a fundamental role in the early development of the neutral theory [ 17].

"Of course, all species have their own value and functional importance, regardless of their history.