Sentence examples for fundamental defect in from inspiring English sources

A fatty liver frequently coincides with metabolic abnormalities, and studies suggest that it may be one of the causes of insulin resistance, the fundamental defect in Type 2 diabetes.

Some economists believe the worst is over and that the recent setback was caused mainly by a need to "correct" excess inventories, not any fundamental defect in the economy.

We speculate that reduced proliferation and vascularity in Perk-deficient insulinomas is caused by a fundamental defect in function in the secretory pathway that we have recently discovered in beta-cells.

Histological examination of paraffin sections showed that none of the ViaatlacZ -/- newborns examined had inflated their lungs at birth indicating an early fundamental defect in respiratory function (data not shown).

Insulin resistance (IR) represents a fundamental defect in type 2 diabetes and precedes the disease for many years (2).

An alternative method to address the fundamental defect in cystic fibrosis is the development of genotype-specific small-molecule drugs that modulate CFTR function.

This is why I said earlier that insulin resistance may be a fundamental underlying defect in many cancers, as it is in type 2 diabetes and heart disease.

But the stalemate "had also concealed the fundamental defects in the U.N.'s machinery".

Some papers appearing in the two leading clinical journals of our specialty have fundamental defects in design, statistical analysis, and reporting.

As we reduce the rate of people dying from heart disease and cancer, we face another threat, and that's neurodegenerative diseases, like Alzheimer's and Parkinson's disease, that are caused by fundamental defects in protein folding.

In response, some point out that there are many examples of poor design in nature: The human tailbone, tonsils and other vestigial organs, and even fundamental defects in the design of the eye.