Sentence examples for fundamental defect from inspiring English sources

In this letter he wrote, "The fundamental defect is a want of power in Congress…the confederation itself is defective and requires to be altered; it is neither fit for war, nor peace".

Working mostly with mice, researchers have already deployed the tool to correct the genetic errors responsible for sickle-cell anemia, muscular dystrophy, and the fundamental defect associated with cystic fibrosis.

A fatty liver frequently coincides with metabolic abnormalities, and studies suggest that it may be one of the causes of insulin resistance, the fundamental defect in Type 2 diabetes.

The plan "is full of good intentions," the Turin daily La Stampa wrote in a front-page editorial on Wednesday, "but it has a fundamental defect: It doesn't give more funding for the education and training of young Italians".

I think that even he would concede that there are occasionally bad apples in the dog world — dogs that are the way they are because of some fundamental defect — the same way the human world occasionally gives us a Jeffrey Dahmer.

"Berlusconi says yes to everything and then Tremonti [the finance minister] says no," says another former cabinet minister, who thinks Mr Berlusconi has damaged Italy but nevertheless describes him as "charming, magnetic, one of the most intelligent people I have met".The fundamental defect of Mr Berlusconi's governing style is that he often confuses private interests with public ones.

This is why I said earlier that insulin resistance may be a fundamental underlying defect in many cancers, as it is in type 2 diabetes and heart disease.

But the stalemate "had also concealed the fundamental defects in the U.N.'s machinery".

The latest version suffers from the same fundamental defects that led this page to oppose a slightly more grandiose version in 1997.

Would anyone have believed a promise by Mr Berlusconi, say, to cut spending in five years' time?The real criticism of the euro zone's response is that it took too long to deal with its fundamental defects.

Nevertheless, I argue in this article that the equipoise principle suffers from fundamental defects.