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The more fundamental challenge will be upholding the principles of impartiality -- aid based on need -- and independence -- aid free of political interest.
Although it is often stated that the availability of biobricks will be the major bottleneck in advances in synthetic biology, a more fundamental challenge will likely be to completely map and design a functional cell and optimize it to the level of robust performance required for commercial operation (Stephanopoulos, 2012).
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This is the problem we are addressing today, and it certainly will remain the fundamental challenge that will keep us all busy and united.
"The most fundamental challenge for Fox will be dealing with the enormously profound expectations Mexicans have of him after winning the election," said Luis Rubio, the director of Cidac, an economic and political research organization in Mexico City.
Thus an even more fundamental challenge for carnivore conservation will be to build community tolerance for predators by reducing the need for retaliatory predator control and by improving benefit sharing from well managed trophy hunting [15].
A fundamental challenge in this endeavor will be choosing methods that can tease apart complex evolutionary histories among taxa.
It is, loosely speaking, the fundamental reason why their title challenge will almost certainly come up short and what a remarkable late passage of play that was from a Crystal Palace side that had looked suspiciously in end-of-season mode for three quarters of this match.
That is the power of his insistence that even Obama has made only halting progress toward a progressive ideal, and that to go further requires a more fundamental challenge to the system, and that will take bravery and guts.
Meeting this challenge will take a fundamental shift back in our spending priorities.
The fundamental challenge for implementation of this approach will be the integration of computational biology, evolutionary, and ecosystem-based approaches, found at the intersection of more traditional mathematics and biology departments, into biomedical and public health research, as others have noted (Koopman and Lynch 1999; Levins and Lopez 1999; McMichael 1999).
However, since no single intervention will be sufficient, the fundamental challenge is maximizing the collective effectiveness of the optimal set of interventions.
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