Sentence examples for fundamental challenge when from inspiring English sources

In a consequence, choosing a threshold for converting mRNA levels of the studied genes into the binary results appeared to be a fundamental challenge when higher specificity resulted in lower sensitivity.

More importantly, insulator surfaces pose fundamental challenges when aiming for on-surface reactions.

This fundamental feature poses an important challenge when trying to describe biological phenomena by means of mechanistic mathematical models: a set of differential/algebraic equations which, for some value of the parameters, interpolates experimental data, cannot be considered a plausible model if it does not possess the aforementioned robustness properties.

A fundamental challenge in digital control arises when the controlled plant is subjected to a fast disturbance dynamics but is only equipped with a relatively slow sensor.

The fundamental challenge has become to specify when and for whom the manner in which children retain information from stories has been changed by electronic storybooks, for better and for worse.

The field of synthetic biology is emerging to solve some of the fundamental challenges that arise when we try to harness the powerful, yet extremely complex, capabilities of natural biomolecular systems.

This clinical scenario, particularly when played out in the ICU, reflects a fundamental challenge to the multidisciplinary health-care team: getting the whole team to play from the same page of music.

This is a potentially fundamental challenge to the 20th Century production line mentality that ends in bulging landfill when consumer goods run out of useful (or fashionable) life.

So when Jason Kincaid says Tim O'Reilly says Steve Jobs is trying to build a fundamental challenge to the Web, I have to be careful.

A fundamental challenge in the design of Wireless Sensor Networks (WSNs) is to maximize their lifetimes especially when they have a limited and non-replenishable energy supply.

"We face a fundamental challenge in economic reform," Turnbull said.