Sentence examples for fundamental cellular pathways from inspiring English sources

If PPT1 does have a role during embryonic neurogenesis, then the elucidation of the fundamental cellular pathways requiring PPT1 during development will be critical.

Drosophila has provided a powerful genetic system in which to elucidate fundamental cellular pathways in the context of a developing and functioning nervous system.

Mitochondria are double-membrane cytoplasmic organelles that house a number of fundamental cellular pathways and functions, including, the aerobic synthesis of ATP [1]; the biosynthesis of heme, ketones, and uridine [2], calcium trafficking, and control of apoptosis [3].

Various stimuli activate JNK, which participates in the regulation of fundamental cellular pathways such as autophagy and apoptosis [ 49].

The pathway enrichment analysis indicated the bidirectional genes at the genome level are conserved in certain pathways, such as the DNA repair and some other fundamental cellular pathways.

Therefore, Drosophila has emerged as a powerful model system for the elucidation of fundamental cellular pathways relevant to both intestinal stem cell biology and to aging.

Now, our findings reveal that the metabolic and proteotoxic stress responses, two fundamental cellular stress pathways, are interconnected through AMPK and HSF1.

Aside from induction of cold-shock proteins however, little is known of other fundamental cellular stress pathways in relation to cooling and their potential relevance to hypothermic preconditioning (Hofman et al., 2012, van der Harg et al., 2014).

With increasing scrutiny on how fundamental cellular stress-response pathways impact survival and expansion of dormant tumor cells, autophagy has emerged as an attractive target against dormant tumor cells.

In melanoma, several models of resistance to TGF-β growth suppressor signals have been suggested, also in view of the dysregulation of fundamental cellular effectors and signaling pathways [9, 22].

The p21-activated kinases signal through a number of cellular pathways fundamental to growth, differentiation and apoptosis.