It wasn't until the 1960s that British drinking culture began to shift in fundamental ways, and the beginnings of the era of Peak Booze can be seen.
"At its core," Mr. Bush said, "this issue forces us to confront fundamental questions about the beginnings of life and the ends of science.
At its core, this issue forces us to confront fundamental questions about the beginnings of life and the ends of science.
The inexorable march of science is altering the rules of life itself, creating dilemmas that, as President Bush said of stem cell research, "forces us to confront fundamental questions about the beginnings of life and the ends of science".
The first decades of the second half of the 19th century represented the beginnings of a fundamental shift in the still-young nations of Latin America.
Dennis Ross, the director of the Washington Institute for Near East Policy and a former negotiator in the Clinton administration, said: "I think we're now seeing the beginnings of a fundamental transformation in the Likud.
Indeed some foreign and Japanese commentators think they have detected the beginnings of a fundamental change.In May Nissan, Japan's second-biggest car maker, was rumoured to be selling Nissan Diesel, its lorry-making subsidiary, to Germany's Daimler-Benz, though nothing has yet been settled.
Members of the protagonist family represent the main trends in the political life of the country: the Wafd party, with its heroes Saad Zaghloul and Mustafa Nahhas (the party with which Mahfouz associated himself), the burgeoning socialist movement as exemplified by the writings of Salama Mousa, and the beginnings of a fundamental Islamic movement.
What's really going on is the beginnings of a fundamental philosophical debate.
But for now, there are signs that China's unbearable air has become the catalyst for at least the beginnings of a fundamental change in direction.
