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Identification of biological functions was based on a Fischer's exact test which calculated a p-value determining the probability that each biological function assigned to each signature is due to chance alone.
The calculation of the potential functions was based on a reduced model for protein structures where the pair-wise interactions of residues are represented by distance-dependent interactions between centroids.
The ranking for biological functions was based on the number of SDEG involved.
The analysis of mitochondrial functions was based on adaptation of protocols developed for mitochondrial diagnostics in cultured skin fibroblasts [25], [27], [28], [32].
The conversion of signaling and regulatory interactions into Boolean functions was based on described functions reported in the literature (the rationale for the choice of less obvious Boolean functions for certain interactions is explained in the Additional file 2).
In fact the formulation of many thermodynamic functions was based on specifying the controlled thermodynamic parameters under which the reaction takes place.
Similar(54)
First of all, the model structure and value functions are based on value-based MCDA [ 3, 7].
Wherever possible, these functions were based on known (evidence-based) regional or national impact models.
Cerebral functions are based on the functional interactions between multiple distinct specialized regions of the brain.
Both functions were based on a set of experimental results using the technique of experimental design.
These functions are based on the evaluation of an approximation of the population Fisher information matrix.
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CEO of Professional Science Editing for Scientists @ prosciediting.com