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As with T cells, B cells contain functionally distinct subsets with regulatory functions, such as the production of anti-inflammatory IL-10 [ 99, 100].
These cells contribute in a major fashion to gastrointestinal innate immune functions such as the production of antimicrobial peptides and mucus and maintenance of epithelial integrity.
In addition, the feed vaccine significantly induced T cell effector functions, such as the production of IFN-γ and activation of the transcription factor that induces its expression, T-bet.
Co-inhibitory and co-stimulatory immune checkpoint receptors are required for full T-cell activation and effector functions such as the production of cytokines.
VEGF is a protective factor for endothelial cells, regulating multiple biological functions, such as the production of vasoactive mediators and the expression of components of the thrombolytic and coagulation pathways.
NK cells have effector cytotoxic activities and immunoregulatory functions such as the production of cytokines such as IFN- γ, TNF-α, and granulocyte-macrophage colony-stimulating factor (GM-CSF) [ 84, 85].
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Likewise, Eomes performs similar functions such as promoting the production of cytotoxic effector molecules and IFN- γ [ 22].
Previous studies showed that muscle functions, such as the amplitude of force production, are closely related to architectural characteristics (e.g. CSA) (Lieber 2002).
Negative impacts largely occurred on agricultural landscapes through the introduction of new functions, such as the area of exploitation, service buildings and production facilities.
In fact, TGF-β and PGE2 share many immunomodulatory functions, such as the inhibition of IFN-γ, interleukin 2 (IL-2) and IL-12 production [ 50, 51] and macrophage deactivation, suppressing TNF-α and iNOS production [ 52, 53].
Background Skeletal muscle has many vital functions, such as production of locomotion, maintenance of posture, regulation of body temperature, and breathing.
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