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The former manipulation disrupts the abstraction or mental flexibility and the latter sustained attention or perseverance both of which are the major functions of the prefrontal system.
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83 Thus, it is plausible that the expansion of the prefrontal system and of prefrontal-projecting cerebellar lobules in humans 39 also relates to adaptations for articulate speech.
While the insula may be easily grafted onto a neural diagram for the slightly nebulous concept of craving, a recent model 118 places the interoceptive functions of the insula as a thermostat, in a three-system model where the insula represents a gateway between the subcortical reward system and the prefrontal system responsible for decision making and inhibitory control.
It develops and enhances the nine important functions of the prefrontal cortex, which include regulating our body, emotional balance, attuned communication and response flexibility, intuition, empathy, fear modulation, insight and morality.
The monoamines play an important modulatory role in the cognitive functions of the prefrontal cortex (PFC).
We now explore the functions of the prefrontal regions preferentially involved in hierarchical sequence processing.
The Wisconsin Card Sorting Test (WCST) [ 55] was used to evaluate executive functions of the prefrontal cortex.
Second, the results reveal a direct association between a cognitive control system subserving deception and function of the prefrontal cortex.
It has been supposed that particular DTNBP1 alleles increase the risk for schizophrenia and affect cognitive functions mediated by the glutamate neurotransmitter system directly affecting the development, maturation, and adult function of the prefrontal cortex [ 54, 58, 59].
With the development of neuroimaging, many studies have depicted the limbic system in depression, showing changes in the structure and function of the prefrontal cortex, hippocampus, and amygdala [ 4].
The capacity to control impulses that arise from these feelings is a function of the prefrontal cortex.
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