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Th1, Th2, and Th17 cells are effector cells contributing to key functions of the immune response.
For instance, inadequate acquiring of the M2 phenotype and excessive production of anti-inflammatory cytokines can decrease bactericidal and antiviral functions of the immune response and provoke allergic and asthmatic Th2 reactions [ 106, 107] and tumor growth [ 108].
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The resulting increase in the propensity for sleep during illness may play an important role in promoting the function of the immune response and overall recovery.
Nutrients are needed for the normal function of the immune response; whether it is to increase the number of cells capable of fighting viruses, produce antibodies and other key mediators or kill other invading pathogens.
Whilst true presence or absence of disease, given exposure to infection, will be largely a function of the immune response, we have demonstrated that the actual prevalence of disease and the estimable genetic variation between animals will be influenced by variable exposure and the sensitivity of diagnosis.
Selenium plays an important role in preventing impaired function of the immune response [ 43].
These data reveal that C/EBP- β is crucial for the accurate functioning of the immune response, in particular of haemopoietic and lymphoid compartments.
Our results show that how the immune system responds to CMV has a fundamental impact on the phenotype and function of the immune response to mycobacterial antigens in older life.
They have immune modulating effects, in which they work in parallel with other signal arising from direct cell-to-cell contact, providing a communication network involved in everyday function of the immune response [ 50- 52].
The balance between pro-inflammatory and anti-inflammatory cytokines mediates homeostasis in an organism, while the selective regulation and proper functioning of the immune response are important for defense against invading pathogens.
The genes in the list were involved in a variety of functions, including the immune response (e.g. ISGF1 and DDX60), cellular adhesion (e.g. CDC42EP1, FBF1) and neural functions (e.g. TXLNB).
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