Sentence examples for functions of modifications from inspiring English sources
There are two main characteristic functions of modifications: one is to affect the contact between nucleosomes and the interaction between histones and DNA, and the other is the recruitment of nonhistone proteins.
The objective of this study was to evaluate the mechanical and thermal properties of these composites as a function of modification of kenaf fiber by using alkalization and silane-treatments.
To obtain a quantitative measure of global histone turnover as a function of modification status and type of sequence variant, we designed a time course experiment using stable isotope labeling with amino acids in cell culture (SILAC) in conjunction with high-resolution mass spectrometry (MS).
The detailed characterization of NET histone modifications, as accomplished by Liu and colleagues [ 1], invites speculations about the possible functions of these modifications.
Identification of novel pseudouridylation sites is an important first step in elucidating the regulation and functions of these modifications.
Since the types and functions of RNA modifications are largely unknown, nanopore sequencing could spur research in this unexplored area.
Forrest White pointed out that we should now focus on the biological functions of these modifications, truly a grand challenge.
Our results present comprehensive information for future studies on understanding the biological functions of histone modifications in soybean, such as regulating the DNA transcription and DNA repair.
However, in most cases the modifying enzymes are currently not known and thus the biological and cellular functions of these modifications have not been elucidated in detail yet.
Methods that introduce posttranslational modifications in a general, mild, and non-sequence-specific manner using biologically produced peptides have great utility for investigation of the functions of these modifications.
However, the precise mechanistic functions of this modification are still unknown.
