Sentence examples for functions of detoxification from inspiring English sources
The proven direct PhoP targets include nine genes encoding regulators and 21 genes or operons with functions of detoxification, protection against DNA damages, resistance to antimicrobial peptides, and adaptation to magnesium limitation.
A well-established mechanism for AhR function of detoxification starts from its activation by a ligand, usually a dioxin, followed by transport to the cell nucleus, where the AhR forms a heterodimer with ARNT.
These genes are involved in the functioning of detoxification [ 12].
They are mostly insect specific GSTs (Delta and Epsilon) with the potential function of detoxification.
In order to give an overview of the function of detoxification proteins, we collected all the 388 human genes and then explored their annotation of molecular function in Gene Ontology by means of the GOEAST [ 40].
It could also lead to better understanding of the function and evolution of detoxification proteins.
The functions of bacterial NO detoxification machinery depend on oxygen (O2 ), with O2 inhibiting some enzymes, whereas others use it as a substrate.
The functions of ALDH2 include detoxification of acetaldehyde, short chain aliphatic aldehydes, and some aromatic and polycyclic aldehydes [ 44].
Peroxiredoxins, catalase, and glutathione peroxidase are all capable of eliminating H2O2 efficiently [ 25, 26], but exactly how these many mechanisms are coordinated is not fully understood - although a deeper understanding of the functions of specific ROS detoxification enzymes and their interactions with classical phosphorylation-based signal transduction systems is slowly emerging.
Liver is a vital organ responsible for plethora of functions including detoxification, protein synthesis, and the production of biochemicals necessary for the sustenance of life.
Several investigators reported that the abnormal expression of AKR proteins in liver tumor tissues or cells possibly resulted in loss of detoxification functions [33,34].
