The theory, an integration of the work of Charles Darwin (natural selection) and Gregor Mendel (genetics), encompassed the biological processes of gene mutation and recombination, changes in the structure and function of chromosomes, reproductive isolation, and natural selection.
Then, the fitness function of chromosomes will be calculated.
Immunolocalization is an important and efficient tool in studies involving the understanding of genome organization and analysis of the structure and function of chromosomes.
The study of the behavior of these proteins provide information about the function of chromosomes, since part of the control of the genetic information encoded by DNA depends on interactions with proteins.
The use of the immunolocalization technique combined with cytogenetic and epigenetic studies is an indispensable tool and has contributed significantly to the analysis of the structure and function of chromosomes, since it can provide information about the spatial or temporal distribution of a given protein in the nucleus and chromosomes.
In particular, very few gene products have been found to be necessary to maintain structure and function of chromosomes at this level of organization.
However, actin has been shown to be a component of the INO80 chromatin remodeling complex (Shen et al. 2000), the NuA4 histone acetyltransferase complex (Galarneau et al. 2000), and the SWR chromatin remodeling complex (Krogan et al. 2003) and therefore actin is clearly in a position to influence the structure and function of chromosomes.
Where F(G i ) is the value of the fitness function of chromosome G i. Note that the selected chromosomes are still in the population, and as a result, it is entirely likely that a chromosome is selected more than once.
For each locus on the array, a %HL total), which is a direct reflection of the replication time, was calculated and plotted as a function of chromosome coordinate.
