Inspection of the remaining genes in the non-complex-autism group CNVs revealed three additional genes functioning in the same processes (B4GALT1, ARSA, and GALNTL5), for which Prioritizer had determined borderline significance (0.057
The qPCR results showed that 26 of the 43 R2R3-MYB genes were up-regulated under ABA treatment, most of which showed similar patterns to their Arabidopsis orthologs, suggesting that they function in the same processes [ 4].
We also show the shared GO terms from the Gene Ontology database, in order to infer potential PPIs based on their functions in the same process or localization.
This suggests that many of our putative histone-coregulated genes also co-function or participate in the same processes as histone genes.
The putative motifs were found by applying AlignACE to the upstream regions of genes that constituted functional classes in the literature, i.e. classes having similar biochemical functions or participating in the same process.
In order to facilitate the identification of genetic modifiers with the same function or involved in the same process, NeuroGeM provides an ontology-based search functionality that searches for genes by GeneOntology (GO) annotations and the hierarchical structure of GO terms [ 12].
At Lesson.ly, there is zero line drawn in the sand between these two functions of the same process because it is just that, one process.
However, ortholog assignment is not necessarily proof for a function of the encoded proteins in the same process as the ancestral protein.
All three modules for which we did a detailed analysis in this study have each a coherent set of genes, involved in the same process and function.
