Sentence examples for functions in the same pathway as from inspiring English sources
KIAA0141, death-associated protein effector DELE, is a pro-apoptotic protein that functions in the same pathway as caspases 8 and 10, and is functionally enhanced by inflammatory proteins such as TNFα (Harada et al. 2010).
The protein encoded by the NRAS gene functions in the same pathway as KRAS and mutations in this gene have been found in 3% of CRC (http://www.sanger.ac.uk/genetics/CGP/cosmic/). The NRAS gene is highly expressed in CRC (http://www.oncomine.org), hence it is to be expected that tumors with an NRAS mutations are resistant to EGFR targeted therapy.
These findings strongly suggest that rac1 functions in the same pathway as Ret and integrins in regulating the attachment of dendrites to the ECM.
Genetic studies in Arabidopsis have also revealed that RDR6 functions in the same pathway as AGO7 and Asymmetric leaves 1 and 2 (and AS2 AS2) to control adaxial/abaxial patterning in leaves [ 37].
To determine whether the Scc4-conserved patch functions in the same pathway as Chl4, we introduced the scc4 mutationintointo a chl4Δ strain and tested for its effect on plasmid segregation.
Here we report that Gadd45γ is required for testis determination in mice and describe data supporting a model in which GADD45γ functions in the same pathway as MAP3K4 and p38 MAPK during gonadogenesis.
Given that UEV-1 does not appear to be downstream of clathrin-dependent endocytosis, and that GLR-1 colocalizes with RAB-10 in uev-1 mutants, we reasoned that UEV-1 might function in the same pathway as RAB-10.
Moreover, this model does not exclude the possibility that other, as yet uncharacterized, intrinsic determinants function in the same pathway as Ascl1 and could discriminate p3[5HT] from p3[V3].
Taken together, this confirms our finding that ATM and Artemis function in the same pathway as Brca2, Rad51 and Rad54 for repairing radiation-induced DSBs in G2.
