Various lipid pathways are involved in neuronal function and in the metabolism of Aβ and tau.
Another important function of the liver in humans is the metabolism of fatty acids.
It functions in the formation and metabolism of fats and carbohydrates.
Sleep deprivation reduces the metabolism of glucose, which acts as brain food for these functions.
As such, there might be a positive feedback loop involving mitochondrial metabolism and integrin functions in the context of cell movement.
Interestingly, mutant p53 also displays such a gain of function in the context of metabolism.
GYS1 is a member of glycogen synthase family and mainly overexpressed in muscle tissues and as the name refers, it functions in glycogen metabolism.
The enzyme LDH is found in the rodent fetal brain52 where it functions in cellular metabolism.
In chloroplasts, PPR proteins fulfil a variety of functions in RNA metabolism.
Anergic T cells have altered diacylglycerol metabolism, but whether that altered metabolism has a causative function in the induction of T cell anergy is not apparent.
