This endothelial receptor recognizes Lewisx selectively and has been proposed to function in adhesion of tumor cells during metastasis (Coombs et al. 2005; Elola et al. 2007).
These genes have putative functions in adhesion to or the invasion of epithelial cells in C. sakazakii.
The role of ROCK1 function in adhesion to fibronectin has been analysed in rat embryo fibroblasts which, when seeded on fibronectin, displayed significantly higher ROCK1 activity than ROCK2 [11].
CD58 (present on Antigen Presenting Cells) is known to be a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes.
In accordance with the specific functions of basal myoepithelial cells in adhesion of the mammary epithelial bilayer to the basement membrane, integrins and cytoplasmic components of the cell ECM adherens junctions (such as vinculin, α-actinin, focal adhesion kinase and talin) are much more abundant in myoepithelial cells than in luminal epithelial cells [ 39].
CLA is a skin-homing receptor that functions in the adhesion of cells to the vascular endothelium.
Dumpy, along with two other ZP domain proteins, Piopio and Papilotte, function in the adhesion of the apical surface of the Drosophila wing epithelia to the overlying cuticle, and loss of function of each of these three genes results in a blistering phenotype in the wing [23], [24].
In addition, the lipid transport-related genes uniquely represented in the maize silk-specific/preferential dataset included a number of genes encoding LTPs that may function in the adhesion of pollen tubes to the surface of transmitting tract during their growth in the silk.
In view of its function in adhesion, it is considered as an invasion suppressor, which is indeed corroborated by in vitro experiments (Vleminckx et al, 1991).
The integrins are involved in several functions including adhesion of activated endothelial cells with the extracellular matrix, proliferation, migration, and differentiation signals of vascular cells [ 6].
