Likewise, a recent study states the glandular role of the epidermis in the abdominal sternites of Dinoponera lucida (Ponerinae) and among the functions hypothesized for this gland in such species comprise the synthesis, transfer and/or the transformation of the CHCs after production by oenocytes [40].
Note that many of the SNPs we identified herein are found in novel, computationally predicted genes having functions hypothesized on the basis of homology to genes in other species.
Having confirmed the inhibitory activity of NKp44 also in pDCs stimulated with DNA immunocomplexes, we wondered whether NKp44 molecule expressed by pDCs might differ from that expressed by NK cells (where the same receptor activates NK cell functions), hypothesizing, for instance, differences in its intracytoplasmic tail.
The apparent discrepancy may be due to the very function hypothesized for rafts and platforms, that of concentrating certain molecules in closer proximity than they might be in the typical lipid bilayer [21], [24], [25], [29].
Given the proposed role of microvascular disease on cognitive function, particularly cognitive domains that incorporate executive functions, we hypothesized that prevalent systemic CVD would be associated with worse cognitive performance in hemodialysis patients.
Because these genes seem to serve similar functions, we hypothesized that egr-1 may also play a role in aging and stress response and could be another example of a gene that has a protective role during normal aging.
As TIMP-1 displays pleotropic functions, we hypothesized that TIMP-1 expression may serve as a neuroprotective response of astrocytes.
The exaptation or co-option of these elements to provide important cellular functions is hypothesized to have played a powerful force in evolution; however, proven examples are rare.
During peri-operative management, Chappell and colleagues prospectively explored the consequences of acute volume loading on endothelial functions and hypothesized that high-volume infusion could alter endothelial glycocalyx.
As aSyn misfolds and aggregates in PD, and DJ-1 displays chaperone-like functions, we hypothesized that DJ-1 may modulate aSyn aggregation.
Three possible functions were hypothesized: i) MNC could be undifferentiated (immature) cells, [ 25, 26]; ii) MNC could secrete several peptides involved in both mucosal protection and repairing [ 27, 28]; iii) MNC could contain pepsinogen A and C granules [ 29].
