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Although the loss of mitochondrial functions enhanced DOX resistance in both the ccr4Δ and pop2Δ mutants it did not totally eliminate DOX-induced lethality suggesting that survival following DOX exposure is only in part dependent on the maintenance of functional mitochondria.
However, dopamine therapy can have differential effects on the motor and cognitive systems (Cools 2006; MacDonald et al. 2011), with some functions enhanced and others impaired by medication.
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The results show that the choice of specific shape functions enhances the effectiveness of the Rayleigh Ritz method.
These optimization functions enhance and complement the scheduling algorithms while maintaining an adequate QoS performance by modifying average parameters of the different layers in the system.
DM mediated peptide exchange is usually examined in terms of one of its functions, enhancing the release of the prebound peptide.
The V. vulnificus elastase/protease has also been shown to possess dual functions, enhancing vascular permeability and causing hemorrhagic damage [87] [88].
Artificial extension of IRE1's RNAse function enhanced cell survival in the face of ER stress [18], [19].
For each gene, their loss of function enhanced adherens junction defects in zygotic baz mutants during early embryogenesis.
Mutation of PTPN11 in Noonan syndrome and leukaemic cells resulted in gain-of-function enhanced phosphatase activity.
Diabetic ApoE−/−-mice displayed severe impairment of endothelial function, enhanced oxidative stress and increased atherosclerotic lesion formation.
Similar to Figure 1 figure supplement 1A, the square root function enhanced the signal to noise ratio for the resolution range beyond 16.8 Å.
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