Sentence examples for functions as an interaction from inspiring English sources
Indeed, we hypothesize that Tspan9 has multiple simultaneous interacting partners and functions as an interaction 'hub' within tetraspanin microdomains.
By contrast, the GFP-μHD does concentrate at plasma membrane clathrin assemblages, because the domain functions as an interaction hub (Reider et al., 2009; Dergai et al., 2010; Henne et al., 2010; Mulkearns and Cooper, 2012; Umasankar et al., 2012) but, again, does not refashion these atypical coated zones.
TRF2 also functions as a protein protein interaction hub within the telomere interaction network, bringing together signaling molecules from numerous cellular pathways (Kim et al., 2009).
Many proteins which function in both apoptotic and inflammatory signaling cascades contain a caspase recruitment domain (CARD), which functions as a homotypic interaction motif.
The PHc domain is part of the well-characterized DH PH tandem domain, whereas PHn is featured as part of a novel N-terminal PH CC Ex region that functions as a protein interaction module.
As Ctf4 lacks enzymatic activity, potentially limiting its development as a therapeutic target, we exploited its function as a physical interaction hub to rationally predict synthetic lethal interactions between essential Ctf4-binding proteins and CIN cancer gene orthologs.
The ICF model describes the individuals' functioning as a complex interaction between a health condition and contextual factors.
More importantly, it has been suggested that the PH CC Ex region may function as a protein protein interaction module.
This suggests that the region of the SCR N-terminus encoding the octapeptide and LASCY motifs may serve an evolutionarily conserved function as a general interaction interface.
The lack of conserved catalytic residues rules out EssB-N as an enzyme, but rather suggests a function as a protein protein interaction module using the stable modular entity of the protein kinase fold.
The PDZ domain is a small globular module that functions as a protein-protein interaction domain (Harris and Lim 2001; Subbaiah et al. 2011).
