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All these data generated in PC3 cells seem to contradict the traditional belief that the AR functions as a stimulator in prostate tumor growth and metastasis.
Specifically, TGF-β functions as a stimulator in the tumor microenvironment to promote Treg cell proliferation and immune evasion [ 46].
NPY is a neurotransmitter that is predominantly found in the central nervous system, where it functions as a stimulator of feeding behavior and inhibition of anxiety.
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LATS1/LATS2 cooperate with the upstream Mst2 kinase to phosphorylate YAP at Ser-127 and inactivate its function as a stimulator of cell detachment [ 32].
To the best of our knowledge, this is the first report about the THBS3 gene function as a stimulator of tumor progression in osteosarcoma.
The health issue may both function as a stimulator for climate change policies and as an integrator for a diversity of relevant actors and policy fields to start working together.
VEGF was discovered as an endothelial cell mitogen and functions as an angiogenesis stimulator [ 69].
In turn, GH stimulates the production of insulin-like growth factor-I (IGF-I), which functions as a cell cycle stimulator (Macaulay, 1992; Westley and May , 1995.
The function of Cthrc1 as a stimulator of bone formation without affecting bone resorption is very promising, because most types of drugs which are currently used for the treatment of osteoporosis are antiresorptive in nature and insufficient for restoring bone volume in osteoporotic patients [23].
In this context, FGF8b appeared to function as an autocrine stimulator of growth and proliferation.
For heparin to function as an efficient stimulator of thrombin inhibition, higher molecular weight forms of heparin are needed.
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