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IRF-1 functions as a regulator of the interferon system and key transcription factor in the regulation of cell cycle and apoptosis.
Thus, an important role for SOCS1 in vivo is the regulation of IFN-γ signaling, although SOCS1 also functions as a regulator of innate immunity by modulating TLR signaling [ 72, 73].
For example, a fly with an extra set of wings has a defective gene not in the abdominal region but in the thoracic region, which normally functions as a regulator of such mutations.
This finding indicates that DREB1A functions as a regulator of osmoprotectant biosynthesis to enhance stress tolerance.
Atrial natriuretic peptide (ANP) has anti-inflammatory as well as natriuretic effects and serves important functions as a regulator of blood pressure, fluid homeostasis, and inflammation.
Atrial natriuretic peptide (ANP) has natriuretic, diuretic, and vasodilating properties and serves important functions as a regulator of blood pressure and fluid volume homeostasis [8].
The 70-kd heat shock protein is released from cells in response to stress and functions as a regulator of innate immunity.
IL-6 is a multifunctional cytokine which is produced by a large variety of cells and functions as a regulator of immune response, acute phase reactions, and hematopoiesis.
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This suggests that Ro52 interacts with IRF7 post-pathogen recognition and may function as a regulator of IRF7 stability, similarly to its role in regulating IRF3 [13].
Our data provide first insights of S100A10 function as a regulator of the filamentous actin network.
Due to its function as a regulator of drug-metabolizing enzymes and transporters, pregnane X receptor (PXR) represents an important factor involved in drug metabolism.
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