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"It opened a whole new era for understanding how the heart functions as a pump and what goes wrong when it fails to pump efficiently," said Dr. Heinrich Taegtmeyer, a professor of medicine at the University of Texas Health Science Center in Houston.
The pigmented epithelium functions as a pump to remove fluid from the retina, and stimulation with laser spots is thought to stimulate pump function and thereby decrease retinal edema.
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HF is defined as a syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the heart to function as a pump to support a physiological circulation [ 29].
Since ventricular fibrillation completely prevents the heart from functioning as a pump, it quickly brings death unless emergency measures restore the circulation of oxygenated blood throughout the body.
For example, we can use a fan to pump some noxious gas from one room to another, or to the outside of a building; but if we set a fan on the lawn, it may beat the air, but is not (functioning as) a pump.
For the heart to function as a pump, the myocardium must relax following systole.
Heart failure (HF) is a complex clinical syndrome that can result from any cardiac disorder that impairs the ability of the heart to function as a pump.
The aforementioned novel device functions as a passive pump, and could find applications in many systems such as portable direct methanol fuel cells and drug delivery systems.
Because vGluT functions as a filling pump that transports glutamate from the presynaptic cytoplasm into the vesicle lumen [35], it is often considered a molecular marker of glutamatergic neurons in mollusks [23], [24].
We demonstrate that cross-resistance between aminopyrazole and spiroindolone series is mediated by mutations in pfatp4, a gene encoding a P-type ATPase that functions as a Na+/H+ pump at the parasite plasma membrane.
ATPase activity and the formation of phosphointermediates verify the full function of the enzyme: the ATPase is inhibited by vanadate (IC50= 119 μM) and the formation of phosphorylated enzyme intermediates shown by acidic PAGE depends on calcium, indicating that the Synechocystis P-ATPase functions as a calcium pump.
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