Sentence examples for functions as a promoter from inspiring English sources

In contrast, the 5'UTR sequence of the mouse L1 contains tandem repeats of approximately 200-bp monomers that functions as a promoter [13], [14].

With regard to autophagy, p53 functions as a promoter or suppressor according to its subcellular distribution and target effectors.

Taken together, these observations indicate that Cav-1 may functions as a promoter of motility and invasion in HCC.

Such a construct could express spastin only if the region between the first two ATGs functions as a promoter.

If a genomic sequence functions as a promoter, de novo methylation can lead to transcriptional silencing of the downstream gene [ 45, 46].

When activated in the cytoplasm, Syk functions as a promoter of cell growth (Zhou and Geahlen, 2009), consistent with the function postulated in this study.

Together, several lines of evidence suggest a model in which PARP1 functions as a promoter-specific cofactor for NF-κB-dependent gene expression [ 7, 14].

These findings point to a crucial role of poly(ADP-ribosyl)ation in shaping DEK's autoantigenic properties and in its function as a promoter of cell survival.

Based on the study of Li et al. (2006b) who suggested that a 2,640 bp fragment at the 5′ upstream of the SH4 gene had the function of regulating the expression of SH4, we isolated a 2.6-kb fragment, ranging from the position −2,472 to +150, to study its multiple tissue-specific function as a promoter.

However, even under conditions of KAP1 knockdown, none of the tested 3' ends of the ZNF genes functioned as a promoter in the luciferase reporter assays (Figure 2C, 2D).

Among the three PPAR isotypes, PPARδ is distinguished by its ability to function as a promoter of tumorigenesis in many instances [21], and is highly expressed in colon cancer [23], [24], head and neck cancer [25], endometrial cancer [26] and breast cancer [21].