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Thank you for sending your work entitled "Beetle juice strategy: ABC transporter functions as a pacemaker for sequestration of plant glucosides in leaf beetles" for consideration at eLife.
We have changed the title to read: "ABC transporter functions as a pacemaker for the sequestration of plant glucosides in leaf beetles".
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To function as a pacemaker, the intrinsic timing signal from the SCN must be transmitted to different brain regions.
Thus, the circadian clock plays an important role as a pacemaker for various physiological events that occur throughout the day.
In mammals, a population of coupled circadian clock cells in the hypothalamic suprachiasmatic nuclei (SCN) function as a master pacemaker responsible for coordinating circadian oscillators elsewhere in the brain and other tissues with daily light dark cycles (Welsh et al., 2010).
If the ZmCCA1/ZmTOC1 loop functions as the pacemaker (time synchronizer), with this attenuated amplitude, its relative contribution to signaling diurnal output genes should also be severely reduced in ears.
These children therefore require close monitoring, not only of ECG and of adequate functioning of a pacemaker, but also of ventricular function.
It indicates that autapse excitation plays an important role in regulating the collective behaviors of neurons as a pacemaker.
The suprachiasmatic nucleus (SCN) of the hypothalamus functions as the master pacemaker to initiate daily synchronization according to the photoperiod, in turn determines the phase of peripheral cellular clocks through a variety of signaling relays, including endocrine rhythms and metabolic cycles.
Some experts view it as a pacemaker for the brain that disrupts negative circuitry.
The best position I could hope for as a pacemaker would be between 20th and 30th.
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