Sentence examples for functions as a driver from inspiring English sources

While the exact signaling pathways governing this phenomenon are not yet fully elucidated, it is clear that oxidative stress-induced autophagy functions as a driver of muscle wasting [ 96].

Our data suggest that targeted treatment of CRC patients with AURKA inhibitors may improve OS, provided that within a given tumour AURKA functions as a driver of the carcinogenic process rather than as a passenger of the mitotic machinery.

DOI: http://dx.doi.org/10.7554/eLife.00999.008 Previous studies implicated that the Hpo pathway effector Yki functions as a driver of proliferation in both ECs and ISCs and damage-induced ISC proliferation via both cell-autonomous and non-cell-autonomous mechanisms (Karpowicz et al., 2010; Ren et al., 2010; Shaw et al., 2010).

Technological change – Romer demonstrates how knowledge can function as a driver of long-term economic growth.

Inequality causes shorter, unhealthier and unhappier lives; it increases the rate of teenage pregnancy, violence, obesity, imprisonment and addiction; it destroys relationships between individuals born in the same society but into different classes; and its function as a driver of consumption depletes the planet's resources.

His work has focused on confronting the rapid pace of technological change by showing how knowledge can function as a driver of long-term economic growth.

Conversely, an amplified or deleted gene that is upregulated or downregulated only minimally, in a statistically non-significant manner in patient data can still function as a driver gene if it alters the expression of its network neighbourhood.

Despite a wealth of knowledge on genetic mutations leading to the oncogenic activation of AKT and a growing appreciation for the ability of AKT to coordinately regulate mRNA translation, the extent to which deregulated AKT translational control functions as an oncogenic driver remains largely undefined.

Indeed, exon 6 IL7R mutations in pediatric T-ALL cases conferred cytokine-independent cell growth and promoted tumor cell transformation, confirming their functional significance as a "driver," gain-of-function mutation.

This same theme carries Tragedy Girls, in which doing it for the likes functions as a comically thin driver for a gruesome killing spree.

This is likely because of a limited understanding of whether the SHH pathway functions as a key tumor driver in these other tumor types as it does in BCC.