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In 2004 SUMOylation was primarily thought to function within the nucleus, so the identification of a number of SUMO-immunoreactive proteins on the mitochondria was unexpected.
In addition, since Hdac6 appears to function within the nucleus in only a subset of cell types (stem and progenitor cells), the effect of Hdac6 loss on gene regulation is likely much more limited than that of Tip60 loss throughout the embryo.
Recent data from Lobie and colleagues have suggested that the extracellular domain of the GHr, also known as the growth hormone binding protein (GHBP), exists and functions within the nucleus in a manner independent of the ligand [ 9].
Recent reports indicate that bcl-2 also resides in the nuclear membrane and may even function within the nucleus [21] [24].
10 11 IL-33 functions within the nucleus through its association with chromatin in vivo.
As ICP0 is thought to function primarily within the nucleus, the role of localization in dictating the function of ICP0 has been understudied.
Within those, the team discovered smaller objects similar in size to the nuclei of blood cells in modern birds.
Some authors have reported that bcl-2 may reside, and even elicit a function, within the nucleus [21] [23], modulating the transactivity of several transcription factors [35], [36].
It is well known that central transmission of vago-vagal reflex within the nucleus of solitary tract (NST) plays an important role in the regulation of gastrointestinal functions.
Chromosome Human DNA is stored in 23 pairs of chromosomes within the nucleus of each cell.
Thresholded images were counted for positive foci within the nucleus of NeuN-positive neurons.
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